Immunobiology of Influenza Virus Infection: Approaches for an Emerging Zoonotic Disease|Scientific Program

Immunobiology of Influenza Virus Infection: Approaches for an Emerging Zoonotic Disease

July 29-31, 2007

The University of Georgia Center for Continuing Education Conference Center and Hotel, Athens, GA

Organizers: Ralph A. Tripp, S. Mark Tompkins, Frederick D. Quinn, and Harry W. Dickerson

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July 29 - Keynote Address

5 to 6 p.m.	Registration and Reception	Conference Registration Desk Hill Atrium

6 to 7 p.m.	Session I – Welcome and introduction: Meeting organizers (Dickerson, Quinn, Tompkins, & Tripp) Keynote Address: Dr. Peter Doherty, Nobel Prize in Medicine, 1996; University of Melbourne (Introduction by Ralph Tripp) The relationship between influenza primary and memory CD8+ T cell responses and novel developments in CD8 T+ cell vaccine design for influenza virus.
7 to 9 p.m.	Reception	Pecan Tree Courtyard

July 30 - "Host response to Influenza & Disease Intervention Strategies"

7 to 8 a.m.	Light Buffet Breakfast Set up posters (Poster session I)	Magnolia Ballroom
7 to 9 a.m.	Registration open	Conference Registration Desk
8 to 10 a.m.	Session II – Host response to viral infection Chairs: Ralph Tripp, Daniel Perez Thomas Braciale Dendritic cell subsets and the T cell response to influenza David Woodland Regulation of CD8+ T cell recall responses to influenza virus infection David Topham Short talk: Protection of effector CD8 T cells from apoptosis in the airways during acute influenza infection
10 to 10:30 a.m.	Coffee break Time to view posters	Hill Atrium
10:30 a.m. to Noon	Session II – Host response to viral infection (continued) Jack Bennink Influence of the Sympathetic Nervous System on Anti-Influenza Immunity Stephen Turner Factors that influence selection of antigen-specific T cell repertoire diversity to acute viral infection
Noon to 1 p.m.	Light (Sandwich) Buffet lunch Time to view posters	Magnolia Ballroom
1 to 3 p.m.	Session III – Host response & intervention strategies Chairs: Richard Webby, David Topham Richard Compans Novel vaccines and transcutaneous delivery systems for influenza vaccines Ruben Donis Influenza vaccine development for pandemic preparedness: a library approach Anthony DeFougerelles Short talk: RNA interference as a novel strategy for prevention and treatment of pandemic influenza
3 to 3:30 p.m.	Coffee break Time to view posters	Hill Atrium
3:30 to 6 p.m.	Session III – Host response & intervention strategies (continued) Jon Karpilow Short Talk: RNAi as a tool for basic research in virology Paul Thomas Short talk: Prediction and analysis of immunodominance hierarchies in influenza infection using a discrete mathematical model S. Mark Tompkins Short talk: M2 immunization induces broad antibody responses and protection against influenza virus challenge Scott Laster Short talk: Terameprocol inhibits production of cytokines and inflammatory lipids from RAW 264.7 cells infected with influenza A Elena Govorkova Short talk: Antiviral Drugs for Control of H5N1 Influenza Virus Infection: Preclinical Data on Efficacy and Resistance John Treanor TBA
6 to 8 p.m.	Poster Session I with refreshments	Hill Atrium

July 31 - "Influenza biology and disease transmission"

7 to 8 a.m.	Light Buffet Breakfast Set up posters (Poster session II)	Magnolia Ballroom
8 to 10 a.m.	Session IV – Influenza biology Chair: Jack Bennink, Terrence Tumpey Jacqueline Katz Influenza A Virus Pathogenesis and Transmissibility in Mammals Richard Webby Host Susceptibilities to H5N1 Influenza Daniel Perez Short talk: Japanese quail and molecular markers of host range for H9N2 influenza A viruses
10 to 10:30 a.m.	Coffee break Time to view posters	Hill Atrium
10:30 a.m. to Noon	Session IV – Influenza biology (continued) David Suarez Avian Influenza Biology and Disease Transmission James Stevens Short talk: Influenza hemagglutinin receptor binding and structure analysis David Steinhauer Short talk: Analysis of Residues Near the Fusion Peptide in the Influenza Hemagglutinin Structure for Roles in Triggering Membrane Fusion
Noon to 1 p.m.	Light (Sandwich) Buffet lunch Time to view posters	Magnolia Ballroom
1 to 3 p.m.	Session V – Public Health Challenges Chairs: Richard Compans, David Steinhauer Robert Nordgren Current Avian Influenza Vaccination Practices for Poultry and other Animal Species Egbert Mundt Short talk: Molecular characterization of highly pathogenic H5N1 during epidemic in Germany Terrence Tumpey Short talk: Pathogenicity and transmissibility of the 1918 influenza virus in mice and ferrets Cynda Crawford Short talk: Syndromic serosurveillance for canine influenza virus infection of dogs in the U.S. Andreas Handel Short talk: Influenza resistant to neuraminidase inhibitors: the danger of its generation and spread
3 to 3:30 p.m.	Coffee break Time to view posters	Hill Atrium
3:30 to 6 p.m.	Session V – Public Health Challenges (continued) Marcia Blackman Naïve precursor T cell frequencies impact responses to influenza virus infection in aged mice and result in impaired CD8 T cell responses to immunodominant epitopes P. Christopher Roberts Short talk: The Viral “Predisposed State”: Host pathogen Responses Leading To Viral:Bacterial Synergistic Enhancement Of Disease Walter Orenstein Influenza Vaccine Policy and Development
5:30 to 6 p.m.	POINT / COUNTERPOINT: A discussion of the conference by Peter Doherty, University of Melbourne, and Barry Rouse, University of Tennessee.

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